FBMB e.V.
Forschungsverbund BioMedizin
Bielefeld/OWL FBMB e.V.

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Publications

Regenerative Medicine

Regenerative Medicine

  1. 6

    Schmidt KE, Höving AL, Nowak K, an Mey N, Kiani Zahrani S, Nemeita B, Riedel L, Majewski A, Kaltschmidt B, Knabbe C, Kaltschmidt C.

    Serum Induces the Subunit-Specific Activation of NF-κB in Proliferating Human Cardiac Stem Cells. International Journal of Molecular Sciences. 2024; 25(7):3593. https://doi.org/10.3390/ijms25073593
    Ansehen
  2. 5

    Schmidt KE, Höving AL, Kiani Zahrani S, Trevlopoulou K, Kaltschmidt B, Knabbe C, Kaltschmidt C.

    Serum-Induced Proliferation of Human Cardiac Stem Cells Is Modulated via TGFβRI/II and SMAD2/3. International Journal of Molecular Sciences. 2024; 25(2):959. https://doi.org/10.3390/ijms25020959
    Ansehen
  3. 4

    Höving A, Schmidt K, Kaltschmidt B, Kaltschmidt C*, Knabbe C*

    The Role of Blood-Derived Factors in Protection and Regeneration of Aged Tissues, (2022) Int J Mol Sci. 23(17):9626 doi:10.3390/ijms23179626
  4. 3

    Höving A, Sielemann K, Greiner J, Kaltschmidt B, Knabbe C *, Kaltschmidt C *

    Transcriptome analysis reveals high similarities between adult human cardiac stem cells and neural crest-derived stem cells, (2020) Biology 9(12):435 doi: 10.3390/biology9120435
  1. 2

    Höving A, Schmidt K, Merten M, Hamidi J,Rott AK, Faust I, Johannes Greiner J , Gummert J, Kaltschmidt B, Kaltschmidt C *, Knabbe C

    Blood Serum stimulates p38-mediated proliferation and changes in global gene expression of adult human cardiac stem cells, (2020) Cells 9(6):1472 doi: 10.3390/cells9061472
  2. 1

    Höving AL, Schmitz J, Schmidt KE, Greiner JFW, Knabbe C, Kaltschmidt B, Grünberger A, Kaltschmidt C.

    Human Blood Serum Induces p38-MAPK- and Hsp27-Dependent Migration Dynamics of Adult
    Human Cardiac Stem Cells: Single-Cell Analysis via a Microfluidic-Based Cultivation Platform.
    Biology (Basel). 2021 Jul 24;10(8):708. doi: 10.3390/biology10080708. PMID: 34439941; PMCID:
    PMC8389316.

Regenerative Medicine - Projekt 3

  1. 6

    Niemann T, Joneleit J, Storm J, Nacke T, Wähnert D, Kaltschmidt C, Vordemvenne T*, Kaltschmidt B*.

    (* equal contribution). Analyzing Sex-Specific Dimorphism in Human Skeletal Stem Cells. Cells 2023, 12, 2683. https://doi.org/10.3390/cells12232683
  2. 5

    Merten M*, Greiner J*, Niemann T*, Grosse Venhaus M, Kronenberg D, Stange R, Wähnert D, Kaltschmidt C, Vordemvenne T*, Kaltschmidt B*

    (*equal contribution). Human Sex Matters: Y-Linked Lysine Demethylase 5D Drives Accelerated Male Craniofacial Osteogenic Differentiation. Cells. 2022; 11(5): 823.
    ANSEHEN
    Ansehen
  3. 4

    Wähnert D, Greiner J, Brianza S, Kaltschmidt C, Vordemvenne T, Kaltschmidt B.

    Strategies to Improve Bone Healing: Innovative Surgical Implants Meet Nano-/Micro-
    Topography of Bone Scaffolds. Biomedicines. 2021 Jun 28;9(7):746. doi: 10.3390/
    biomedicines9070746. PMID: 34203437; PMCID: PMC8301359.
  4. 3

    Wähnert D, Koettnitz J, Merten M, Kronenberg D, Stange R, Greiner JFW, Kaltschmidt C, Vordemvenne T, Kaltschmidt B.

    Spongostan leads to Increased Regeneration of a Rat Calvarial Critical Size Defect Com-pared to Nanobone and Actifuse, Materials (Basel). 2021 Apr 14;14(8):1961. doi: 10.3390/ma14081961.
  1. 2

    Vordemvenne T, Wähnert D, Koettnitz J, Merten M, Fokin N, Becker A, Büker B, Vogel A, Kronenberg D, Stange R, Wittenberg G, Greiner JF, Hütten A, Kaltschmidt C, Kaltschmidt B.

    Bone regeneration: A Novel Osteoinductive Function of Spongostan by the Interplay between Its Nano- and Microtopography, Cells. 2020Mar 7;9(3), doi:10.3390/cells9030654.
  2. 1

    Greiner JF, Gottschalk M, Fokin N, Büker B, Kaltschmidt BP, Dreyer A, Vordemvenne T, Kaltschmidt C, Hütten A, Kaltschmidt B.

    Natural and synthetic nanopores directing osteogenic differentiation of human stem cells, Nanomedicine. 2019 Apr;17:319-328. doi: 10.1016/j.nano.2019.01.018. Epub 2019 Feb 14.

Cancer Research

Cancer Stem Cell Research

  1. 24

    Helweg LP*, Storm J*, Witte KE, Schulten W, Wrachtrup L, Janotte T, Kitke A, Greiner JFW, Knabbe C, Kaltschmidt B, Simon M*, Kaltschmidt C*.

    (*equal contribution). Targeting Key Signaling Pathways in Glioblastoma Stem Cells for the Development of Efficient Chemo- and Immunotherapy. Int J Mol Sci. 2022 Oct 26;23(21):12919. doi: 10.3390/ijms232112919. PMID: 36361720; PMCID: PMC9659205.
  2. 23

    Kaltschmidt B, Helweg LP, Greiner JFW, Kaltschmidt C.

    NF-κB in neurodegenerative dise ases: Recent evidence from human genetics. Front Mol Neurosci. 2022 Aug 2;15:954541. doi: 10.3389/fnmol.2022.954541. PMID: 35983068; PMCID: PMC9380593.
  3. 22

    Helweg LP*, Windmöller BA*, Burghardt L, Storm J, Förster C, Wethkamp N, Wilkens L, Kaltschmidt B, Banz-Jansen C*, Kaltschmidt C*

    (*equal contribution). The Diminishment of Novel Endometrial Carcinoma-Derived Stem-like Cells by Targeting Mitochondrial Bioenergetics and MYC. International Journal of Molecular Sciences. 2022; 23(5): 2426.
    Ansehen
  4. 21

    Kaltschmidt B, Witte KE, Greiner JFW, Weissinger F, Kaltschmidt C.

    Targeting NF-κB Signaling in Cancer Stem Cells: A Narrative Review. Biomedicines. 2022 Jan 25;10(2):261. DOI: 10.3390/biomedicines10020261.
  1. 20

    Witte KE, Pfitzenmaier J, Storm J, Lütkemeyer M, Wimmer C, Schulten W, Czaniera N, Geisler M, Förster C, Wilkens L, Knabbe C, Mertzlufft F, Kaltschmidt B, Schulte am Esch J, Kaltschmidt C.

    Analysis of Several Pathways for Efficient Killing of Prostate Cancer Stem Cells: A Central Role
    of NF-κB RELA. Int J Mol Sci. 2021 Aug 18;22(16):8901. doi: 10.3390/ijms22168901.
    PMID: 34445612; PMCID: PMC8396252.
  2. 19

    Kaltschmidt C, Greiner JFW, Kaltschmidt B.

    The Transcription Factor NF-κB in Stem Cells and Development. Cells. 2021 Aug 10;10(8):2042.
    doi: 10.3390/cells10082042. PMID: 34440811; PMCID: PMC8391683.
  3. 18

    Windmöller BA, Beshay M, Helweg LP, Flottmann C, Beermann M, Förster C, Wilkens L, Greiner JFW, Kaltschmidt C, Kaltschmidt B.

    Novel Primary Human Cancer Stem-Like Cell Populations from Non-Small Cell Lung Cancer:
    Inhibition of Cell Survival by Targeting NF-κB and MYC Signaling. Cells. 2021 Apr 27;10(5):1024.
    doi: 10.3390/cells10051024. PMID: 33925297; PMCID: PMC8145874.
  4. 17

    Witte KE, Hertel O, Windmöller BA, Helweg LP, Höving AL, Knabbe C, Busche T, Greiner JFW, Kalinowski J, Noll T, Mertzlufft F, Beshay M, Pfitzenmaier J, Kaltschmidt B, Kaltschmidt C, Banz-Jansen C, Simon M.

    Nanopore Sequencing Reveals Global Transcriptome Signatures of Mitochondrial and Ribo-somal Gene Expressions in Various Human Cancer Stem-like Cell Populations. Cancers (Ba-sel). 2021 Mar 6;13(5):1136. doi: 10.3390/cancers13051136. PMID: 33800955; PMCID: PMC7962028.
  1. 16

    Witte KE, Slotta C, Lütkemeyer M, Kitke A, Coras R, Simon M, Kaltschmidt C, Kaltschmidt B.

    PLEKHG5 regulates autophagy, survival and MGMT expression in U251-MG glioblastoma cells. Sci Rep. 2020 Dec 14;10(1):21858. doi: 10.1038/s41598-020-77958-3. PMID: 33318498; PMCID: PMC7736842.
  2. 15

    Schulte Am Esch J, Windmöller BA, Hanewinkel J, Storm J, Förster C, Wilkens L, Krüger M, Kaltschmidt B, Kaltschmidt C.

    Isolation and Characterization of Two Novel Colorectal Cancer Cell Lines, Containing a Sub-population with Potential Stem-Like Properties: Treatment Options by MYC/NMYC Inhibition. Cancers (Basel). 2020 Sep 10;12(9):2582. doi: 10.3390/cancers12092582. PMID: 32927768; PMCID: PMC7564713.
  3. 14

    Schürmann M, Greiner JFW, Volland-Thurn V, Oppel F, Kaltschmidt C, Sudhoff H, Kaltschmidt B.

    Stem Cell-Induced Inflammation in Cholesteatoma is Inhibited by the TLR4 Antagonist LPS-RS. Cells. 2020 Jan 14;9(1):199. doi: 10.3390/cells9010199. PMID: 31947538; PMCID: PMC7017370.
  4. 13

    Windmöller BA, Greiner JFW, Förster C, Wilkens L, Mertzlufft F, Schulte Am Esch J, Kalt-schmidt B, Kaltschmidt C, Beshay M.

    A typical carcinoid of the lung - a case report with pathological correlation and propagation of the cancer stem cell line BKZ1 with synaptophysin expression. Medicine (Baltimore). 2019 Dec;98(49):e18174. doi: 10.1097/MD.0000000000018174. PMID: 31804333; PMCID: PMC6919531.
  1. 12

    Kaltschmidt C, Banz-Jansen C, Benhidjeb T, Beshay M, Förster C, Greiner J, Hamelmann E, Jorch N, Mertzlufft F, Pfitzenmaier J, Simon M, Schulte Am Esch J, Vordemvenne T, Wähnert D, Weissinger F, Wilkens L, Kaltschmidt B.

    A Role for NF- κB in Organ Specific Cancer and Cancer Stem Cells. Cancers (Basel). 2019 May 11;11(5):655. doi: 10.3390/cancers11050655. PMID: 31083587; PMCID: PMC6563002.
  2. 11

    Slotta C, Storm J, Pfisterer N, Henkel E, Kleinwächter S, Pieper M, Ruiz-Perera LM, Greiner JFW, Kaltschmidt B, Kaltschmidt C.

    IKK1/2 protect human cells from TNF-mediated RIPK1-dependent apoptosis in an NF-κB-independent manner. Biochim Biophys Acta Mol Cell Res. 2018 Aug;1865(8):1025-1033. doi: 10.1016/j.bbamcr.2018.04.003. Epub 2018 Apr 7. PMID: 29630899.
  3. 10

    Nagel J, Wöllner S, Schürmann M, Brotzmann V, Müller J, Greiner JF, Goon P, Kaltschmidt B, Kaltschmidt C, Sudhoff H.

    Stem cells in middle ear cholesteatoma contribute to its pathogenesis. Sci Rep. 2018 Apr 18;8(1):6204. doi: 10.1038/s41598-018-24616-4. PMID: 29670222; PMCID: PMC5906547.
  4. 9

    Kaltschmidt B, Greiner JFW, Kadhim HM, Kaltschmidt C.

    Subunit-Specific Role of NF-κB in Cancer. Biomedicines. 2018 Apr 17;6(2):44. doi: 10.3390/biomedicines6020044. PMID: 29673141; PMCID: PMC6027219.
  1. 8

    Slotta C, Schlüter T, Ruiz-Perera LM, Kadhim HM, Tertel T, Henkel E, Hübner W, Greiner JFW, Huser T, Kaltschmidt B, Kaltschmidt C.

    CRISPR/Cas9-mediated knockout of c-REL in HeLa cells results in profound defects of the cell cycle. PLoS One. 2017 Aug 2;12(8):e0182373. doi: 10.1371/journal.pone.0182373. PMID: 28767691; PMCID: PMC5540532.
  2. 7

    Kaus A, Widera D, Kassmer S, Peter J, Zaenker K, Kaltschmidt C, Kaltschmidt B.

    Neural stem cells adopt tumorigenic properties by constitutively activated NF-kappaB and subsequent VEGF up-regulation. Stem Cells Dev. 2010 Jul;19(7):999-1015. doi: 10.1089/scd.2009.0416. PMID: 20184430.
  3. 6

    Pasdziernik M, Kaltschmidt B, Kaltschmidt C, Klinger C, Kaufmann M.

    On the cytotoxicity of HCR-NTPase in the neuroblastoma cell line SH-SY5Y. BMC Res Notes. 2009 Jun 11;2:102. doi: 10.1186/1756-0500-2-102. PMID: 19519914; PMCID: PMC2700126.
  4. 5

    Widera D, Kaus A, Kaltschmidt C, Kaltschmidt B.

    Neural stem cells, inflammation and NF-kappaB: basic principle of maintenance and repair or origin of brain tumours? J Cell Mol Med. 2008 Apr;12(2):459-70. doi: 10.1111/j.1582-4934.2007.00208.x. Epub 2007 Dec 20. PMID: 18182066; PMCID: PMC3822535.
  1. 4

    Widera D, Mikenberg I, Kaltschmidt B, Kaltschmidt C.

    Potential role of NF- kappaB in adult neural stem cells: the underrated steersman? Int J Dev Neurosci. 2006 Apr-May;24(2-3):91-102. doi: 10.1016/j.ijdevneu.2005.11.017. Epub 2006 Jan 18. PMID: 16413989.
  2. 3

    Lang K, Drell TL 4th, Lindecke A, Niggemann B, Kaltschmidt C, Zaenker KS, Entschladen F.

    Induction of a metastatogenic tumor cell type by neurotransmitters and its pharmacological inhibition by established drugs. Int J Cancer. 2004 Nov 1;112(2):231-8. doi: 10.1002/ijc.20410. PMID: 15352035.
  3. 2

    Schwamborn J, Lindecke A, Elvers M, Horejschi V, Kerick M, Rafigh M, Pfeiffer J, Prüllage M, Kaltschmidt B, Kaltschmidt C.

    Microarray analysis of tumor necrosis factor alpha induced gene expression in U373 human glioblastoma cells. BMC Genomics. 2003 Nov 25;4(1):46. doi: 10.1186/1471-2164-4-46. PMID: 14641910; PMCID: PMC317285.
  4. 1

    Kaltschmidt B, Kaltschmidt C, Hofmann TG, Hehner SP, Dröge W, Schmitz ML.

    The pro- or anti-apoptotic function of NF-kappaB is determined by the nature of the apoptotic stimulus. Eur J Biochem. 2000 Jun;267(12):3828-35. doi: 10.1046/j.1432-1327.2000.01421.x. PMID: 10849002.

Cancer Research on tumors of the lung (EvKB)

  1. 5

    Mohammed H Hassan, Sawsan Abuhamdah, Mohamed Abdel-Bary, Mohammed Wahman, Tarek Hamdy Abd-Elhamid, Morris Beshay, Karam Mosallam, Bakheet E M Elsadek.

    Circulating and local nuclear expression of survivin and fibulin-3 genes in discriminating be-nign from malignant respiratory diseases: correlation analysis. Biosci Rep 2021 Jan 29;41(1):BSR20203097. doi: 10.1042/BSR20203097.
  2. 4

    Mertzlufft

    Huge typical pulmonary carcinoid presented with gigantism syndrome. Gen Thorac Cardio-vasc Surg. 2021 Feb;69(2):371-374. doi: 10.1007/s11748-020-01445-9. Epub 2020 Jul 28
  3. 3

    Morris Beshay, Fritz Mertzlufft, Hans Werner Kottkamp, Marc Reymond, Ralph Alexander Schmid, Detlev Branscheid, Thomas Vordemvenne

    Analysis of risk factors in thoracic trauma patients with a comparison of a modern trauma centre: a mono-centre study. World J Emerg Surg. 2020 Jul 31;15(1):45. doi: 10.1186/s13017-020-00324-1.
  4. 2

    Nadja Lehwald-Tywuschik*, Fabian Steinfurth, Feride Kröpil, Andreas Krieg, Hülya Sarikaya, Wolfram Trudo Knoefel, Martin Krüger, Tahar Benhidjeb, Morris Beshay*, Jan Schulte am Esch.

    Dorsal Track Control (DTC): a modified surgical technique for Atraumatic Handling of the Dis-tal Esophagus for esophagojejunostomy. Accepted for Pub. in the Journal of Gastric Cancer - Decision on Manuscript ID jgc-2019-0060.R1 on the 21.09.2019.
  1. 1

    Hoksch B, Rufer B, Gazdhar A, Bilici M, Beshay M, Gugger M, Schmid RA.

    Taurolidine in the prevention and therapy of lung metastases. Eur J Cardiothorac Surg. 2009 Dec;36(6):1058-63. Epub 2009 Oct 21. PubMed PMID: 19850492.

All Publications

  1. 43

    Schmidt KE, Höving AL, Kiani Zahrani S, Trevlopoulou K, Kaltschmidt B, Knabbe C, Kaltschmidt C.

    Serum-Induced Proliferation of Human Cardiac Stem Cells Is Modulated via TGFβRI/II and SMAD2/3. International Journal of Molecular Sciences. 2024; 25(2):959. https://doi.org/10.3390/ijms25020959
    Ansehen
  2. 42

    Schmidt KE, Höving AL, Nowak K, an Mey N, Kiani Zahrani S, Nemeita B, Riedel L, Majewski A, Kaltschmidt B, Knabbe C, Kaltschmidt C.

    Serum Induces the Subunit-Specific Activation of NF-κB in Proliferating Human Cardiac Stem Cells. International Journal of Molecular Sciences. 2024; 25(7):3593. https://doi.org/10.3390/ijms25073593
    Ansehen
  3. 41

    Niemann T, Joneleit J, Storm J, Nacke T, Wähnert D, Kaltschmidt C, Vordemvenne T*, Kaltschmidt B*.

    (* equal contribution). Analyzing Sex-Specific Dimorphism in Human Skeletal Stem Cells. Cells 2023, 12, 2683. https://doi.org/10.3390/cells12232683
  4. 40

    Kaltschmidt B, Witte KE, Greiner JFW, Weissinger F, Kaltschmidt C.

    Targeting NF-κB Signaling in Cancer Stem Cells: A Narrative Review. Biomedicines. 2022 Jan 25;10(2):261. DOI: 10.3390/biomedicines10020261.
  1. 39

    Merten M*, Greiner J*, Niemann T*, Grosse Venhaus M, Kronenberg D, Stange R, Wähnert D, Kaltschmidt C, Vordemvenne T*, Kaltschmidt B*

    (*equal contribution). Human Sex Matters: Y-Linked Lysine Demethylase 5D Drives Accelerated Male Craniofacial Osteogenic Differentiation. Cells. 2022; 11(5): 823.
    Ansehen
  2. 38

    Helweg LP*, Windmöller BA*, Burghardt L, Storm J, Förster C, Wethkamp N, Wilkens L, Kaltschmidt B, Banz-Jansen C*, Kaltschmidt C*

    (*equal contribution). The Diminishment of Novel Endometrial Carcinoma-Derived Stem-like Cells by Targeting Mitochondrial Bioenergetics and MYC. International Journal of Molecular Sciences. 2022; 23(5): 2426.
    Ansehen
  3. 37

    Ruiz-Perera LM, Höving AL, Schmidt KE, Cenan S, Wohllebe M, Greiner JFW, Kaltschmidt C, Simon M, Knabbe C, Kaltschmidt B.

    Neuroprotection Mediated by Human Blood Plasma in Mouse Hippocampal Slice Cultures and
    in Oxidatively Stressed Human Neurons. Int J Mol Sci. 2021 Sep 3;22(17):9567. doi: 10.3390/
    ijms22179567. PMID: 34502475; PMCID: PMC8430756.
  4. 36

    Witte KE, Pfitzenmaier J, Storm J, Lütkemeyer M, Wimmer C, Schulten W, Czaniera N, Geisler M, Förster C, Wilkens L, Knabbe C, Mertzlufft F, Kaltschmidt B, Schulte am Esch J, Kaltschmidt C.

    Analysis of Several Pathways for Efficient Killing of Prostate Cancer Stem Cells: A Central Role
    of NF-κB RELA. Int J Mol Sci. 2021 Aug 18;22(16):8901. doi: 10.3390/ijms22168901.
    PMID: 34445612; PMCID: PMC8396252.
  1. 35

    Kaltschmidt C, Greiner JFW, Kaltschmidt B.

    The Transcription Factor NF-κB in Stem Cells and Development. Cells. 2021 Aug 10;10(8):2042.
    doi: 10.3390/cells10082042. PMID: 34440811; PMCID: PMC8391683.
  2. 34

    Höving AL, Schmitz J, Schmidt KE, Greiner JFW, Knabbe C, Kaltschmidt B, Grünberger A, Kaltschmidt C.

    Human Blood Serum Induces p38-MAPK- and Hsp27-Dependent Migration Dynamics of Adult
    Human Cardiac Stem Cells: Single-Cell Analysis via a Microfluidic-Based Cultivation Platform.
    Biology (Basel). 2021 Jul 24;10(8):708. doi: 10.3390/biology10080708. PMID: 34439941; PMCID:
    PMC8389316.
  3. 33

    Wähnert D, Greiner J, Brianza S, Kaltschmidt C, Vordemvenne T, Kaltschmidt B.

    Strategies to Improve Bone Healing: Innovative Surgical Implants Meet Nano-/Micro-
    Topography of Bone Scaffolds. Biomedicines. 2021 Jun 28;9(7):746. doi: 10.3390/
    biomedicines9070746. PMID: 34203437; PMCID: PMC8301359.
  4. 32

    Asghari E, Kiel A, Kaltschmidt BP, Wortmann M, Schmidt N, Hüsgen B, Hütten A, Knabbe C, Kaltschmidt C, Kaltschmidt B.

    Identification of Microorganisms from Several Surfaces by MALDI-TOF MS: <I>P. aeruginosa</I>
    Is Leading in Biofilm Formation. Microorganisms. 2021 May 4;9(5):992. doi:10.3390/
    microorganisms9050992. PMID: 34064414; PMCID: PMC8147854.
  1. 31

    Windmöller BA, Beshay M, Helweg LP, Flottmann C, Beermann M, Förster C, Wilkens L, Greiner JFW, Kaltschmidt C, Kaltschmidt B.

    Novel Primary Human Cancer Stem-Like Cell Populations from Non-Small Cell Lung Cancer:
    Inhibition of Cell Survival by Targeting NF-κB and MYC Signaling. Cells. 2021 Apr 27;10(5):1024.
    doi: 10.3390/cells10051024. PMID: 33925297; PMCID: PMC8145874.
  2. 30

    Höving A, Schmidt K, Merten M, Hamidi J,Rott AK, Faust I, Johannes Greiner J , Gummert J, Kaltschmidt B, Kaltschmidt C *, Knabbe C

    Blood Serum stimulates p38-mediated proliferation and changes in global gene expression of adult human cardiac stem cells, (2020) Cells 9(6):1472 doi: 10.3390/cells9061472
  3. 29

    Höving A, Sielemann K, Greiner J, Kaltschmidt B, Knabbe C *, Kaltschmidt C *

    Transcriptome analysis reveals high similarities between adult human cardiac stem cells and neural crest-derived stem cells, (2020) Biology 9(12):435 doi: 10.3390/biology9120435
  4. 28

    Höving A, Schmidt K, Kaltschmidt B, Kaltschmidt C*, Knabbe C*

    The Role of Blood-Derived Factors in Protection and Regeneration of Aged Tissues, (2022) Int J Mol Sci. 23(17):9626 doi:10.3390/ijms23179626
  1. 27

    Greiner JF, Gottschalk M, Fokin N, Büker B, Kaltschmidt BP, Dreyer A, Vordemvenne T, Kaltschmidt C, Hütten A, Kaltschmidt B.

    Natural and synthetic nanopores directing osteogenic differentiation of human stem cells, Nanomedicine. 2019 Apr;17:319-328. doi: 10.1016/j.nano.2019.01.018. Epub 2019 Feb 14.
  2. 26

    Vordemvenne T, Wähnert D, Koettnitz J, Merten M, Fokin N, Becker A, Büker B, Vogel A, Kronenberg D, Stange R, Wittenberg G, Greiner JF, Hütten A, Kaltschmidt C, Kaltschmidt B.

    Bone regeneration: A Novel Osteoinductive Function of Spongostan by the Interplay between Its Nano- and Microtopography, Cells. 2020Mar 7;9(3), doi:10.3390/cells9030654.
  3. 25

    Wähnert D, Koettnitz J, Merten M, Kronenberg D, Stange R, Greiner JFW, Kaltschmidt C, Vordemvenne T, Kaltschmidt B.

    Spongostan leads to Increased Regeneration of a Rat Calvarial Critical Size Defect Com-pared to Nanobone and Actifuse, Materials (Basel). 2021 Apr 14;14(8):1961. doi: 10.3390/ma14081961.
  4. 24

    Helweg LP, Storm J, Witte KE, Schulten W, Wrachtrup L, Janotte T, Kitke A, Greiner JFW, Knabbe C, Kaltschmidt B, Simon M, Kaltschmidt C.

    Targeting Key Signaling Pathways in Glioblastoma Stem Cells for the Development of Efficient Chemo- and Immunotherapy. Int J Mol Sci. 2022 Oct 26;23(21):12919. doi: 10.3390/ijms232112919. PMID: 36361720; PMCID: PMC9659205.
  1. 23

    Kaltschmidt B, Helweg LP, Greiner JFW, Kaltschmidt C.

    NF-κB in neurodegenerative dise ases: Recent evidence from human genetics. Front Mol Neurosci. 2022 Aug 2;15:954541. doi: 10.3389/fnmol.2022.954541. PMID: 35983068; PMCID: PMC9380593.
  2. 22

    Witte KE, Hertel O, Windmöller BA, Helweg LP, Höving AL, Knabbe C, Busche T, Greiner JFW, Kalinowski J, Noll T, Mertzlufft F, Beshay M, Pfitzenmaier J, Kaltschmidt B, Kaltschmidt C, Banz-Jansen C, Simon M.

    Nanopore Sequencing Reveals Global Transcriptome Signatures of Mitochondrial and Ribo-somal Gene Expressions in Various Human Cancer Stem-like Cell Populations. Cancers (Ba-sel). 2021 Mar 6;13(5):1136. doi: 10.3390/cancers13051136. PMID: 33800955; PMCID: PMC7962028.
  3. 21

    Witte KE, Slotta C, Lütkemeyer M, Kitke A, Coras R, Simon M, Kaltschmidt C, Kaltschmidt B.

    PLEKHG5 regulates autophagy, survival and MGMT expression in U251-MG glioblastoma cells. Sci Rep. 2020 Dec 14;10(1):21858. doi: 10.1038/s41598-020-77958-3. PMID: 33318498; PMCID: PMC7736842.
  4. 20

    Schulte Am Esch JSA, Windmöller BA, Hanewinkel J, Storm J, Förster C, Wilkens L, Krüger M, Kaltschmidt B, Kaltschmidt C.

    Isolation and Characterization of Two Novel Colorectal Cancer Cell Lines, Containing a Sub-population with Potential Stem-Like Properties: Treatment Options by MYC/NMYC Inhibition. Cancers (Basel). 2020 Sep 10;12(9):2582. doi: 10.3390/cancers12092582. PMID: 32927768; PMCID: PMC7564713.
  1. 19

    Schürmann M, Greiner JFW, Volland-Thurn V, Oppel F, Kaltschmidt C, Sudhoff H, Kalt-schmidt B.

    Stem Cell-Induced Inflammation in Cholesteatoma is Inhibited by the TLR4 Antagonist LPS-RS. Cells. 2020 Jan 14;9(1):199. doi: 10.3390/cells9010199. PMID: 31947538; PMCID: PMC7017370.
  2. 18

    Windmöller BA, Greiner JFW, Förster C, Wilkens L, Mertzlufft F, Schulte Am Esch J, Kalt-schmidt B, Kaltschmidt C, Beshay M.

    A typical carcinoid of the lung - a case report with pathological correlation and propagation of the cancer stem cell line BKZ1 with synaptophysin expression. Medicine (Baltimore). 2019 Dec;98(49):e18174. doi: 10.1097/MD.0000000000018174. PMID: 31804333; PMCID: PMC6919531.
  3. 17

    Kaltschmidt C, Banz-Jansen C, Benhidjeb T, Beshay M, Förster C, Greiner J, Hamelmann E, Jorch N, Mertzlufft F, Pfitzenmaier J, Simon M, Schulte Am Esch J, Vordemvenne T, Wähnert D, Weissinger F, Wilkens L, Kaltschmidt B.

    A Role for NF- κB in Organ Specific Cancer and Cancer Stem Cells. Cancers (Basel). 2019 May 11;11(5):655. doi: 10.3390/cancers11050655. PMID: 31083587; PMCID: PMC6563002.
  4. 16

    Slotta C, Storm J, Pfisterer N, Henkel E, Kleinwächter S, Pieper M, Ruiz-Perera LM, Greiner JFW, Kaltschmidt B, Kaltschmidt C.

    IKK1/2 protect human cells from TNF-mediated RIPK1-dependent apoptosis in an NF-κB-independent manner. Biochim Biophys Acta Mol Cell Res. 2018 Aug;1865(8):1025-1033. doi: 10.1016/j.bbamcr.2018.04.003. Epub 2018 Apr 7. PMID: 29630899.
  1. 15

    Nagel J, Wöllner S, Schürmann M, Brotzmann V, Müller J, Greiner JF, Goon P, Kaltschmidt B, Kaltschmidt C, Sudhoff H.

    Stem cells in middle ear cholesteatoma contribute to its pathogenesis. Sci Rep. 2018 Apr 18;8(1):6204. doi: 10.1038/s41598-018-24616-4. PMID: 29670222; PMCID: PMC5906547.
  2. 14

    Kaltschmidt B, Greiner JFW, Kadhim HM, Kaltschmidt C.

    Subunit-Specific Role of NF-κB in Cancer. Biomedicines. 2018 Apr 17;6(2):44. doi: 10.3390/biomedicines6020044. PMID: 29673141; PMCID: PMC6027219.
  3. 13

    Slotta C, Schlüter T, Ruiz-Perera LM, Kadhim HM, Tertel T, Henkel E, Hübner W, Greiner JFW, Huser T, Kaltschmidt B, Kaltschmidt C.

    CRISPR/Cas9-mediated knockout of c-REL in HeLa cells results in profound defects of the cell cycle. PLoS One. 2017 Aug 2;12(8):e0182373. doi: 10.1371/journal.pone.0182373. PMID: 28767691; PMCID: PMC5540532.
  4. 12

    Kaus A, Widera D, Kassmer S, Peter J, Zaenker K, Kaltschmidt C, Kaltschmidt B.

    Neural stem cells adopt tumorigenic properties by constitutively activated NF-kappaB and subsequent VEGF up-regulation. Stem Cells Dev. 2010 Jul;19(7):999-1015. doi: 10.1089/scd.2009.0416. PMID: 20184430.
  1. 11

    Pasdziernik M, Kaltschmidt B, Kaltschmidt C, Klinger C, Kaufmann M.

    On the cytotoxicity of HCR-NTPase in the neuroblastoma cell line SH-SY5Y. BMC Res Notes. 2009 Jun 11;2:102. doi: 10.1186/1756-0500-2-102. PMID: 19519914; PMCID: PMC2700126.
  2. 10

    Widera D, Kaus A, Kaltschmidt C, Kaltschmidt B.

    Neural stem cells, inflammation and NF-kappaB: basic principle of maintenance and repair or origin of brain tumours? J Cell Mol Med. 2008 Apr;12(2):459-70. doi: 10.1111/j.1582-4934.2007.00208.x. Epub 2007 Dec 20. PMID: 18182066; PMCID: PMC3822535.
  3. 9

    Widera D, Mikenberg I, Kaltschmidt B, Kaltschmidt C.

    Potential role of NF- kappaB in adult neural stem cells: the underrated steersman? Int J Dev Neurosci. 2006 Apr-May;24(2-3):91-102. doi: 10.1016/j.ijdevneu.2005.11.017. Epub 2006 Jan 18. PMID: 16413989.
  4. 8

    Lang K, Drell TL 4th, Lindecke A, Niggemann B, Kaltschmidt C, Zaenker KS, Entschladen F.

    Induction of a metastatogenic tumor cell type by neurotransmitters and its pharmacological inhibition by established drugs. Int J Cancer. 2004 Nov 1;112(2):231-8. doi: 10.1002/ijc.20410. PMID: 15352035.
  1. 7

    Schwamborn J, Lindecke A, Elvers M, Horejschi V, Kerick M, Rafigh M, Pfeiffer J, Prüllage M, Kaltschmidt B, Kaltschmidt C.

    Microarray analysis of tumor necrosis factor alpha induced gene expression in U373 human glioblastoma cells. BMC Genomics. 2003 Nov 25;4(1):46. doi: 10.1186/1471-2164-4-46. PMID: 14641910; PMCID: PMC317285.
  2. 6

    Kaltschmidt B, Kaltschmidt C, Hofmann TG, Hehner SP, Dröge W, Schmitz ML.

    The pro- or anti-apoptotic function of NF-kappaB is determined by the nature of the apoptotic stimulus. Eur J Biochem. 2000 Jun;267(12):3828-35. doi: 10.1046/j.1432-1327.2000.01421.x. PMID: 10849002.
  3. 5

    Mohammed H Hassan, Sawsan Abuhamdah, Mohamed Abdel-Bary, Mohammed Wahman, Tarek Hamdy Abd-Elhamid, Morris Beshay, Karam Mosallam, Bakheet E M Elsadek.

    Circulating and local nuclear expression of survivin and fibulin-3 genes in discriminating be-nign from malignant respiratory diseases: correlation analysis. Biosci Rep 2021 Jan 29;41(1):BSR20203097. doi: 10.1042/BSR20203097.
  4. 4

    Beshay M, Gutierrez F, Windmöller BA, Förster C, Mertzlufft F.

    Huge typical pulmonary carcinoid presented with gigantism syndrome. Gen Thorac Cardio-vasc Surg. 2021 Feb;69(2):371-374. doi: 10.1007/s11748-020-01445-9. Epub 2020 Jul 28
    Ansehen
  1. 3

    Beshay M, Mertzlufft F, Kottkamp HW, Reymond M, Schmid RA, Branscheid D, Vordemvenne T

    Analysis of risk factors in thoracic trauma patients with a comparison of a modern trauma centre: a mono-centre study. World J Emerg Surg. 2020 Jul 31;15(1):45. doi: 10.1186/s13017-020-00324-1.
    Ansehen
  2. 2

    Lehwald-Tywuschik N, Steinfurth F, Kröpil F, Krieg A, Sarikaya H, Knoefel WT, Krüger M, Benhidjeb T, Beshay M, Schulte am Esch J

    Lehwald-Tywuschik N, Steinfurth F, Kröpil F, Krieg A, Sarikaya H, Knoefel WT, Krüger M, Benhidjeb T, Beshay M, Schulte Am Esch J. Dorsal Track Control (DTC): A Modified Surgical Technique for Atraumatic Handling of the Distal Esophagus in Esophagojejunostomy. J Gastric Cancer. 2019 Dec;19(4):473-483. doi: 10.5230/jgc.2019.19.e35
    Ansehen
  3. 1

    Hoksch B, Rufer B, Gazdhar A, Bilici M, Beshay M, Gugger M, Schmid RA.

    Taurolidine in the prevention and therapy of lung metastases. Eur J Cardiothorac Surg. 2009 Dec;36(6):1058-63. Epub 2009 Oct 21. PubMed PMID: 19850492.